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Cardiac myocytes are the most physically energetic cells in the body. They are highly specialized high-oxygen-content cells that house a large number of mitochondria. They occupy as much as 75% of the cardiac mass, but constitute only about one third of the total cell number in the heart. Differentiated cardiac myocytes have little capacity to proliferate; however, hypertrophic growth has been shown to respond to alpha1-adrenergic stimuli via the Ras/MEK pathway. All cardiac myocytes are capable of spontaneous rhythmic depolarization and repolarization of their membranes. Contraction of cardiac myocytes is myogenic, which is independent of nervous stimulation. There is a complex network of signals in cardiac myocytes regulating the rhythmic pumping of the heart. Cardiac myocyte hypertrophy and apoptosis have been implicated in the loss of contractile function during heart failure. A better understanding of the cardiac signaling network will help reveal the cellular mechanisms leading to cardiac myocyte death.
MCM from ScienCell Research Laboratories are isolated from postnatal day 2 or postnatal day 8 C57BL/6 mouse heart. MCM are cryopreserved at P0 and delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MCM are characterized by immunofluorescence with antibodies specific to smooth muscle actin and/or sacromeric alpha-actinin. MCM are negative for mycoplasma, bacteria, yeast, and fungi. MCM are guaranteed to further culture under the conditions provided by ScienCell Research Laboratories; however, MCM are not recommended for expanding or long-term cultures since the cells do not proliferate in culture.
Recommended Medium
It is recommended to use Cardiac Myocyte Medium-serum free (CMM-sf, Cat. #6101) for culturing MCM in vitro.
货号 | M6200-57 |
产地 | 北美 |
缩写 | MCM |
规格 | 1 x 10^6 cells/vial |
用途 | 科研 |
储存 | 液氮 |
运输 | 干冰 |
小鼠细胞系统
小鼠细胞系统
货号 | 产品名称 | 规格 | 价格 | 指令 | |
M4200 | 小鼠肾系膜细胞 | 5 x 10^5 cells/vial | $446 | + | |
M4200-57 | 小鼠肾系膜细胞 | 5 x 10^5 cells/vial | $470 | + | |
M5300 | 小鼠肝星状细胞 | 5 x 10^5 cells/vial | $477 | + | |
M5300-57 | 小鼠肝星状细胞 | 5 x 10^5 cells/vial | $544 | + | |
M5340 | 小鼠肝巨噬细胞 | 1 x 10^6 cells/vial | $372 | + | |
M5340-57 | 小鼠肝巨噬细胞 | 1 x 10^6 cells/vial | $417 | + | |
M5540 | 小鼠脾细胞 | 10 x 10^6 cells/vial | $198 | + | |
M5540-25 | 小鼠脾细胞 | 25 x 10^6 cells/vial | $390 | + | |
M5540-57 | 小鼠脾细胞 | 10 x 10^6 cells/vial | $238 | + | |
M5550 | 小鼠脾脏巨噬细胞 | 1 x 10^6 cells/vial | $372 | + | |
M5550-57 | 小鼠脾脏巨噬细胞 | 1 x 10^6 cells/vial | $417 | + | |
M6200 | 小鼠心肌细胞 | 1 x 10^6 cells/vial | $446 | + | |
M6200-57 | 小鼠心肌细胞 | 1 x 10^6 cells/vial | $489 | + | |
M6300 | 小鼠心脏成纤维细胞 | 5 x 10^5 cells/vial | $446 | + | |
M6300-57 | 小鼠心脏成纤维细胞 | 5 x 10^5 cells/vial | $489 | + | |
M7540 | 小鼠胚胎成纤维细胞 | 1 x 10^6 cells/vial | $143 | + | |
M7540-2-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial | $44 | + | |
M7540-2-mt-v10 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 10 vials/pk | $381 | + | |
M7540-2-mt-v20 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 20 vials/pk | $777 | + | |
M7540-2-mt-v5 | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 2 x 10^6 cells/vial. 5 vials/pk | $201 | + | |
M7540-5 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $278 | + | |
M7540-5-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 5 x 10^6 cells/vial | $102 | + | |
M7540-57 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $327 | + | |
M7540-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 1 x 10^6 cells/vial | $28 | + | |
M7570 | 小鼠胚胎成纤维细胞 | 1 x 10^6 cells/vial | $143 | + | |
M7570-5 | 小鼠胚胎成纤维细胞 | 5 x 10^6 cells/vial | $283 | + | |
M7570-5-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 5 x 10^6 cells/vial | $105 | + | |
M7570-mt | 小鼠胚胎成纤维细胞--丝裂霉素处理 | 1 x 10^6 cells/vial | $25 | + |